Reconciling multiple genes trees via segmental duplications and losses
نویسندگان
چکیده
منابع مشابه
Analysis of segmental duplications via duplication distance
MOTIVATION Segmental duplications are common in mammalian genomes, but their evolutionary origins remain mysterious. A major difficulty in analyzing segmental duplications is that many duplications are complex mosaics of fragments of numerous other segmental duplications. RESULTS We introduce a novel measure called duplication distance that describes the minimum number of duplications necessa...
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Gene families are a rich source of information about the way evolution shapes genomes, populations, and phenotypes. This is achieved through evolutionary events such as gene duplication, loss, and horizontal transfer. Accordingly, many computational methods have been developed that model these events. In general, these models typically make the simplifying assumption that population-related eff...
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MOTIVATION Large-scale evolutionary events such as genomic rearrange.ments and segmental duplications form an important part of the evolution of genomes and are widely studied from both biological and computational perspectives. A basic computational problem is to infer these events in the evolutionary history for given modern genomes, a task for which many algorithms have been proposed under v...
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ژورنال
عنوان ژورنال: Algorithms for Molecular Biology
سال: 2019
ISSN: 1748-7188
DOI: 10.1186/s13015-019-0139-6